Certainly the matter was finally adjudicated at Appomatox when my grandfather surrendered after four years and several wounds and walked home.
It is sad in a way that the ninth and 10th amendments are being ignored to death and so there is virtually no remedy for Federal usurpation because the courts have ceded the field to the Liberals and simply will not enforce the amendments. Was it Jefferson who said that the tree of liberty must be watered with revolution every generation? Revolution like secession has become virtually illegal and practically impossible in this modern age in which the federal government has a virtual monopoly on military level arms and I space-age surveillance and eavesdropping.
If we're going to preserve our liberties from the tyranny of the Manchurian Marxist, we're going to have to do it on the soap box and in the ballot box.