Unfortunately, no. But we wouldn't want to do that anyway. Only the Northern section, in fact only Chicago and a few nearby counties. The rest of the state suffers from them far more than those of us in the rest of the country. But we can't do that either, since the Constitution, Art IV, sec. 3, forbids creating a state out of part of a state without permission from that state's legislature.
However Article IV, section 4, mandates (It says the United States "shall") that the United States guarantee to each state a Republican Form of Government, which clearly Illinois does not have. Nor do several other states whose urban dominated legislatutes have run roughshod over the rights of their minority rural and suburban citizens.
So it is possible that Something Could Be Done. If that is the Urban Machines did not also control the US Congress and Presidency.
“But we can’t do that either, since the Constitution, Art IV, sec. 3, forbids creating a state out of part of a state without permission from that state’s legislature.”
West Virgina comes to mind.