My personal preference if access time is not a factor would be a 12 gauge home defense shotgun with 00 buck shot. It reduces the need for shot accuracy (in a time of panic) and you have a 9-15 in 1 shot chance of hitting the perp with a pellet, each of which is equivalent in size to a 33 caliber. If you prefer a pistol, go with something like hydro-shock bullets to maximize damage. Preferences are like opinions, everyone has one.
So what's the problem, they're just hard working immigrants doing crimes that Americans won't do.