In modern times, several classes of antibiotics are effective in treating bubonic plague. These include the aminoglycosides streptomycin and gentamicin, the tetracyclines tetracycline and doxycycline and the fluoroquinolone ciprofloxacin. Patients with plague in the modern era usually recover completely with prompt diagnosis and treatment.
Yes, but there has long been concern among modern public health authorities about the ability to cope with large scale outbreaks of the disease. In particular, there are fears of inadequate supplies and availability of the effective antibiotics in such an event. No one is stocking these antibiotics in the huge quantities that will be necessary in such an event, because we in the modern world have yet to see it. But it is theoretically possible, both in scenarios of biological attacks and quick natural spread of the pneumonic form of the disease in densely populated urban areas.