IF the woman just operates in one state, she has no obligation to collect sales tax for any other state, and no other state has the legal ability to go after her for the sales taxes.
So if she is spending money doing so, she probably had bad business advice from someone who operated physically in more than one state.
Of course, if she travels to other states to do trade shows, that would obligate her to collect sales tax for those states — but that is her choice to do business directly in those states, it has nothing to do with her selling things on the internet.
All I know is what she shared on the air and the task of keeping track of all her sales “destinations”. She shared that it was overwhelming.
Since she was in Washington State and Washington is now a “Streamlined Sales Tax” participating state, she has to keep separate track of every city, county, state, and special taxing district tax rate and amount collected for every sale in the State of Washington and any other state she does business in. Quite a daunting task.