I believe that nuclear event will be on Israel. bin biden said that the American public would not agree with it initially, but would have to support and it will be welcome in the long run.
Once Israel is neutralized, the Arab states will be more open and welcome to the US. That’s my guess on bin biden’s comment.
No, they will not be more open to us. The long term goal, as it has been for centuries, is to destroy the West. That will not have changed if Israel is destroyed; it is just a step.