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There are at least 23 recognized arenaviruses (family _Arenaviridae_, genus _Arenavirus_). The conventional phylogeny of these viruses distinguishes "Old World" from "New World" arenaviruses, i.e., based on geographic distribution.

As are the hantaviruses, each arenavirus is principally associated with rodents of a single or a very few species, thus the basis for their geographic distributions. An unusual exception may be Tacaribe virus, which has been isolated from bats and mosquitoes.

Most New World arenaviruses are not known to cause human illnesses but others cause severe illnesses: Machupo virus (Bolivian hemorrhagic fever), Junin virus (Argentine hemorrhagic fever), Guanarito virus (Venezuelan hemorrhagic fever), Sabia virus (Brazilian hemorrhagic fever), and Chapare virus.

Lassa virus has been shown to cause severe, often fatal, hemorrhagic fevers in human in a wide area of West Africa.

It is now recognized that this virus causes numerous illnesses each year. It will be enlightening when we have news of the identity of the viruses causing these illnesses in Zambia, and now in South Africa.

The investigations are in the hands of the world's most competent people for such studies, Dr. Robert Swanepoel of South Africa's National Institute for Communicable Diseases and collaborating investigators at the U.S. Centers for Disease Control and Prevention.

Therefore, definitive information regarding whether this is a hitherto unrecognized arenavirus or a variant of a recognized arenavirus should be forthcoming relatively soon. Meanwhile, clinical practices to control further spread should suffice.

If the etiologic agent is in fact an arenavirus, ribavirin is presently used for the treatment of Lassa fever.

1 posted on 10/13/2008 4:54:50 AM PDT by Mother Abigail
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To: Mother Abigail

Absolutely fascinating. Thank you.


2 posted on 10/13/2008 10:14:16 AM PDT by 2Jedismom (And as He stands in victory, sin's curse has lost it's grip on me.)
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To: Mother Abigail

Thanks for the ping. At least we know what it is. Lassa fever’s pretty nasty stuff and its cousin sounds even nastier. BTT.


4 posted on 10/13/2008 6:47:21 PM PDT by Billthedrill
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To: Mother Abigail; yefragetuwrabrumuy

Thank you, Mother Abigail.

Ping.


5 posted on 10/13/2008 7:06:43 PM PDT by LucyT
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To: Mother Abigail
The paramedic had contact with [the 1st case, the female from Zambia], and after developing flu-like symptoms and a fever was admitted to Flora clinic. He was subsequently transferred to Morningside Medi-clinic and diagnosed with kidney stones.

One of the very few times a man can count his blessings to have kidney stones.

Thanks for the update ping.

9 posted on 10/14/2008 6:36:06 AM PDT by flutters (God Bless The USA)
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