This is usually when social unrests break out.
The dirty little secret, though, is that the U.S. has always been built on high-end labor, due to the availability of land, and that we have never competed with low-wage labor. In the 1800s, Britain battled us with low-wage labor and eventually lost. So did the Japanese in the 1990s. That's why schemes to "bolster" the rust-belt, manufacturing economies are just silly. The only way we win is to stay ahead of the technology---computers, bio-med, glass, high-tech everything.