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To: allmendream

==Why do you deny that it is mathematically possible to do so, will me finding it change your opinion about anything?

No, I just want to read the entire study to make sure you didn’t miss any data or conclusions that might point to epigenetics or Creation.

I have to go for now. I’ll read the “tide you over” paper when I return.

All the best—GGG


543 posted on 08/15/2008 5:53:29 PM PDT by GodGunsGuts
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To: GodGunsGuts
I found this very interesting, epigenetic changes are commonly ectopic expression mutations, such as those linked to Hsp90 dysfunction that resulted in duplicated vibrissae. Ectopic expression would make sense in an epigenetic basis because the when the methylation of DNA breaks down you get expression of genes that were intended to be shut down.

The conclusion of the paper you cited is especially interesting. They see that epigentic inheritance seems especially transitory, yet conclude that the resulting major changes in body plan that can result could bring about major evolution once the different methylation pattern is established.

http://www.dbmi.columbia.edu/~xiw7002/xiaoyan_files/N_genetics.pdf

Because of the inherent instability of epigenetic inheritance, fixation of an epigenetically-determined phenotype is probably less stable than fixation through a genetic selection mechanism. Waddington, for example, was unable to reduce the frequency of the crossveinless phenotype in negative selection experiments once the phenotype was fixed17. In contrast, after only two or
three generations of negative selection, we observed a complete reversion to wild-type frequency of ectopic outgrowth in our sensitized iso-KrIf-1 strain in the geldanamycin selection experiment (data not shown). Similarly, epigenetic traits such as color
variegation or cold adaptation in plants are unstably inherited18,19. Therefore, a combination of both epigenetic and genetic mechanisms is probably required to explain the rapid changes in body plans that are observed in the fossil record20

549 posted on 08/15/2008 7:07:18 PM PDT by allmendream (If "the New Yorker" makes a joke, and liberals don't get it, is it still funny?)
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