“A setback is an opportunity to begin again more intelligently.”—Henry Ford
I think scientists are beginning to conclude that it is not the amyloid plaques that are causing the dementia but may be a symptom of the deterioration in cognitive function. There are also many cases of autopsied elderly deceased with no diminution of cognitive faculties but plenty of amyloid plaque present in their brain.
Great Henry Ford quote. I agree with your insights about plaque. The other issue that gets overshadowed is that a large percentage of patients with cognitive dysfunction have vascular dementia. If you want to maintain your brain, make sure you treat hypertension and do what you can to maintain overall cardiovascular health.