Any reports of rhabdomyolysis with Red Rice Yeast?
http://www.spacedoc.net/red_yeast_rice.htm
None known
Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement1,2,3,4
David Heber, Ian Yip, Judith M Ashley, David A Elashoff, Robert M Elashoff and Vay Liang W Go
Background: We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the American Heart Association Step I diet using a double-blind, placebo-controlled, prospectively randomized 12-wk controlled trial at a university research center.
Objective: We evaluated the lipid-lowering effects of this red-yeast-rice dietary supplement in US adults separate from effects of diet alone.
Design: Eighty-three healthy subjects (46 men and 37 women aged 3478 y) with hyperlipidemia [total cholesterol, 5.288.74 mmol/L (204338 mg/dL); LDL cholesterol, 3.317.16 mmol/L (128277 mg/dL); triacylglycerol, 0.622.78 mmol/L (55246 mg/dL); and HDL cholesterol 0.782.46 mmol/L (3095 mg/dL)] who were not being treated with lipid-lowering drugs participated. Subjects were treated with red yeast rice (2.4 g/d) or placebo and instructed to consume a diet providing 30% of energy from fat, <10% from saturated fat, and <300 mg cholesterol daily. Main outcome measures were total cholesterol, total triacylglycerol, and HDL and LDL cholesterol measured at weeks 8, 9, 11, and 12.
Results: Total cholesterol concentrations decreased significantly between baseline and 8 wk in the red-yeast-ricetreated group compared with the placebo-treated group [( ± SD) 6.57 ± 0.93 mmol/L (254 ± 36 mg/dL) to 5.38 ± 0.80 mmol/L (208 ± 31 mg/dL); P < 0.001]. LDL cholesterol and total triacylglycerol were also reduced with the supplement. HDL cholesterol did not change significantly.
Conclusions: Red yeast rice significantly reduces total cholesterol, LDL cholesterol, and total triacylglycerol concentrations compared with placebo and provides a new, novel, food-based approach to lowering cholesterol in the general population.
Courtesy of the American Journal of Clinical Nutrition