I don’t know about single installs but, if I copy my dwgs onto my hard drive, unplug my lap top from the network and try to use ACAD (+ third party software) at home, without first ‘checking out’ a liscence it will not allow me to open any dwgs. Caught me a few times, had to drive all the friggin’ way back to the office and do it all over again.
What version do you have?