A guy in my condo building turned me onto Liverite, which comes in both pill or capsule form, which can be bought at most drugstores, or Walmart (where I get mine). I was having some liver pain and my liver count turned out to be slightly elevated (too much bad food). When I went to buy the Liverite, the lady who showed me where it was said that after New Year’s Eve, lots of men would come in and buy a bottle of Liverite, LOL!. That sold me on the product. Went home, started taking it (initially 2 pills 3 times a day; now I just do 2 pills a day), and I almost instantaneously felt better. Check it out. I had amazing results from it. No prescription needed. All natural ingredients.
One note about milk thistle; MT releases toxins from the liver by making the hepatocyte cell membranes of the liver more soluble allowing the release of stored toxins. They are then carried by the bile into the gastric tract. Without something to bind them the bloodstream will just pick them back up and take them back to the liver. Psyllium husk (Metamucil and it's variants) will absorb those toxins in the gut and carry them out.
A good regimen is 30 days of two 00 caps of milk thistle powdered and standardized extract and a normal one day dose of psyllium husk. Taking it every day, year in and year out, is probably not necessary. If you have specific chronic problems (such as you refuse to stop smoking and/or eating saturated fats, that's ME! ... or other factors) 2-3 30 day regimens per year would make sense. For the young (curse them all the brats!) healthy non-self-abusive person who doesn't work around heavy metals or the like it's almost ridiculous to worry about cleansing the liver.