i live a few miles from a huge Amish community. Big time genetic defects. Most they can’t even identify. They just know that “somethin’ ain’t right”.
There was a documentary some years back about birth defects in one of the Amish towns. A Korean doctor had managed to win their trust and persuade them to use his clinic. I can’t seem find the name of the program - tried searching Demonoid but only found Weird Al Yankovik.
Amish lethal microencephaly is one defect:
http://www.genome.gov/10004977
Sketch on p. 3, MRI on p. 4:
http://www3.interscience.wiley.com/cgi-bin/fulltext/94517067/PDFSTART