Posted on 04/14/2008 5:01:48 PM PDT by blam
Thanks Dr. Ben Dover.
I see more neuromuscular complications
with this drug class every day.
If they are going to use this drug
I am convinced that anyone on Lipitor
should be on Coenzyme-Q-10
about 200mg twice a day
I’d rather have neuromuscular complications than advanced prostate cancer.
I agree, Prostate Ca is a very real threat
to those of us of advancing years...
Lipitor still drives me nuts
Like what? I've been on it for 3 years or so and haven't any complaints yet.
Achy muscles
Numb hands or feet
Weaker shoulders or pelvis muscles
In my experience, proximal muscle weakness
is often present, and a patient not complaining of it
They just feel “older”
Cox 2 inhibitors effect on cancer. Read about this years ago and research has been going on for what? twenty years? Now it’s news because “I added Lipitor”? But something big is just 5 years away!
Got a bottle of Celebrex at home
It is my favorite de-achyfier
NSAIDS were supposed to prevent colon cancer in people with familial polyposis, as far as I know this did not pan out in clinical trials.
I wouldn’t hold my breath until the effect is seen in clinical trials and then confirmed with further independent testing.
The nagging thought is how many cardiovascular cases the lawyers will pick up. Give old men Celebrex to old men and most of them with die with cardiovascular events. Of course if you don’t give them Celebrex and most of them will die of cardiovacular events but that won’t stop the lawyers.
What does the Coenzyme-Q-10 do?
What are the benefits of CoQ10 for Lipitor users? For users of other statins?
Time to go to bed. I have old men repeating in brain.
I took my first dose of Celebrex two weeks ago, after seeing an Ortho Dr about a painful hip that was waking me up several times every night.
THE NEXT DAY I was able to walk down two steep flights of stairs without pain. Good stuff!
Coenzyme-Q-10? What does that do for you?
Coenzyme Q10 is a vitamin-like substance used in the treatment of a variety of disorders primarily related to suboptimal cellular energy metabolism and oxidative injury. Studies supporting the efficacy of coenzyme Q10 appear most promising for neurodegenerative disorders such as Parkinson's disease and certain encephalomyopathies for which coenzyme Q10 has gained orphan drug status. Results in other areas of research, including treatment of congestive heart failure and diabetes
The widespread use of statin drugs is of special concern because they can lower the endogenous levels of Coenzyme Q10, the naturally-occurring form of ubiquinone in humans. Ubiquinone is widely recognized as an essential component of energy metabolism in the electron-transfer system in mitochondrial membranes. At physiological concentrations it is also recognized as an effective lipid-soluble antioxidant
Considering that Coenzyme Q10 is essential for mitochondrial function and antioxidant activity, and since oxidative mechanisms are important in atherogenesis, it can be assumed that a reduction in CoQ10 level may compromise coronary atherosclerosis despite optimal reduction in cholesterol levels by the use of statin drugs.
Pharmaceutical companies that market statin drugs should consider including the described CoQ10 potential depletion in their drug information materials provided to physicians and pharmacists, and they should encourage patients to consult their physician and pharmacist for appropriate supplementation.
ping
See note #17
See note #17
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