And seceding would solve this how?
Well, our Founding Fathers apparently thought it was a good idea.
It wouldn't be a secession. Should the any of the Bill of Rights be abrogated, the entire constitutional contract is negated, not just one little cherry-picked portion. Accordingly, Articles I,II,III, and IV would be just as moot as the Second Amendment, and there'd be nothing left to seceed from, just as the Soviet Union dissolved in 1991.
But as to how- and more importantly, why- it would *solve* the problem:
When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another, and to assume among the powers of the earth, the separate and equal station to which the Laws of Nature and of Nature's God entitle them, a decent respect to the opinions of mankind requires that they should declare the causes which impel them to the separation. ... .
. ... Governments are instituted among Men, deriving their just powers from the consent of the governed, --That whenever any Form of Government becomes destructive of these ends, it is the Right of the People to alter or to abolish it, and to institute new Government, laying its foundation on such principles and organizing its powers in such form, as to them shall seem most likely to effect their Safety and Happiness. Prudence, indeed, will dictate that Governments long established should not be changed for light and transient causes; and accordingly all experience hath shewn, that mankind are more disposed to suffer, while evils are sufferable, than to right themselves by abolishing the forms to which they are accustomed. But when a long train of abuses and usurpations, pursuing invariably the same Object evinces a design to reduce them under absolute Despotism, it is their right, it is their duty, to throw off such Government, and to provide new Guards for their future security.