Yes if you are an accomplished software designer/IT guy/hacker. If you are average joe you cannot buy software off the shelf and make it run on all flavors of Linux/Unix.
L/U is still a engineers/hackers OS not a mainstream OS.
You probably don't have to.
The Ubuntu software repositories contain tens of thousands of programs. All of them work on Ubuntu. RedHat/Fedora/CentOS have about the same number.
If you absolutely must have a proprietary software package installed on your Linux box and your flavor isn't supported you have a couple of options.
Talk to your software dealer. They will probably say that your flavor isn't supported. That doesn't mean it won't work. It probably just needs a one time tweak.