[JoanVarga]

Great story. Everyone knows that a .22 only serves to aggravate the delicate psychological balance of a situation. A .45, however, is single-session therapy.

-Joan

[Oberon]

I tell you what, though... I bet that guy had a headache.

[punster]

“Great story. Everyone knows that a .22 only serves to aggravate the delicate psychological balance of a situation. A .45, however, is single-session therapy.
-Joan”

A .22 LR will work, if you hit the assailant in the eye socket. However, that is a very difficult shot, especially under the stress of a combat situation.

A 9mm, a .40 S&W, .45 ACP, .357 Sig, will generally smash through to disrupt the central nervous system, effecting a permanent cure to violent criminal tendencies.

In revolvers, a .357 Mag, .41 Mag, or a .44 Mag will effect the same cure. I will grant the .44 is getting a bit heavy in recoil for rapid fire control, and there is a bit of a problem with over penetration.