You have had a lot of advice. Since it is occuring in the same file it is probably a sector going bad on the disc. You can try the various malware scans but the first thing I would do is take an image of the hard drive and transfer it to a brand new drive.
Once you have done this, you can do all of the scans or cures you want with the safety of having a back up that not includes your data but also your operating system, drivers and programs.
Saving data is the most important but tracking down and installing all of your programs and drivers is a huge PIA.
If it is just malware, you can use the extra drive as back up in case of trouble.
My 2 cents.
BINGO!