I really enjoyed the chapters in Richard Feynman’s books that talk about his investigation into the shuttle disaster.
It seems that the shuttle is about as safe as they can make it now - about a 1% chance of total loss per flight. That said, 1% can become %100 if the machines are put in situations they weren’t designed for.
It had a buncha crudely drawn missiles flying towards the top of the page and one spiraling down out of control. In the forground is a man in a general's uniform scowling at the dud.
The caption was something like:
Don't give me 99% reliability! Would YOU fly it?
If it were the Shuttle, I would, in a heartbeat!