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To: BlueDragon
“It is not the genes that code for the specific proteins themselves, that induce either, which combination of acetylation, methylation, and phosphorylation, occurs in the octameric complex, now is it?” Blue Dragon

No, all the processes are regulated or accomplished by proteins coded for by genes, and the code used to code for these genes is the Universal Code of Molecular Genetics.

The chemical composition of the complex (phosphorylation of proteins, methylation of DNA, etc) is indeed accomplished by specific proteins coded for by DNA (using the universal code).

Go apparently GGG accomplished his goal to muddy the waters with all these “Codes upon Codes” and got a few people thinking he was talking about an actual code that ran parallel or orthogonal to the Universal Genetic Code. Sorry all those other control mechanisms are either ‘on/off’ or ‘preferentially subset A/preferentially subset B/preferentially subset B/etc’ (as is the case with histone modification which will target it to specific types of genes turning them off).

So there is no circumstance where the Universal Code is abandoned for usage of a different code when turning DNA into protein. If that is what your comments meant then it was completely and totally erroneous. There is often post-transcriptional modification, such that a single ‘gene’ can produce several different protein products, based upon how the message is spliced. But the message is still translated using the Universal Genetic Code.

151 posted on 01/10/2008 7:41:11 AM PST by allmendream ("A Lyger is pretty much my favorite animal."NapoleonD (Hunter 08))
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To: allmendream; GodGunsGuts
When I said;

Another way to say it could be;

Nor was it the the histones alone, that be the root cause of transcription on/off determination, be though as they may, a controlling mechanism of achieving this on/off determination.

You are arguing something else..? But no, not really since you say,

All right...I'm certainly not disagreeing with that...

This very thread is entitled;

Looks very much like a "code within a code", to me. Why does this bother you so much?
The histone 'code', it is assumed, isn't independently self generating or modulating (since it didn't create itself, all by "itself" in the first place!)...which would leave us looking for the actual root of determining influences elsewhere in the genome, now wouldn't it?

You argue "universal code".
Ok, fine.

I, and many others, still see coding within coding, regardless of how much it is proclaimed "there is only one [universal] code, there is only one code!"

156 posted on 01/10/2008 9:49:54 AM PST by BlueDragon (never set out to sea on a boat that has shiny pump handles...)
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