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Sorry Sam, I disagree with your statement "If she loses the nomination to Obama, her career in national politics is over"

It will not be over. Hillary loves power too much, she will either keep her seat in New York and move to the left and become a muck racker (like Babs Boxer) or listen to me here, yes a Supreme Court nominee from an Obama administration. Think about it, she would love to sit on a life time appointment legislating from the bench as much as she could.

I see your point but realize just how large her ego is and that the only reason she holds a senate seat in the first place (which she feels is "beneath her") is to use it as a springboard to what she really hungers for - the White House. After having had a taste of it during Bill's two terms, anything else would be unacceptable.

The failure to even get the nomination will be devastating to her and she'll have an absolute meltdown if and when that happens - mark my words. Now if she is somehow able to pull out the nomination and loses in November, she'll hang on to that senate seat for another chance in 2012. But if she doesn't win the nomination and the realization sets in that she won't have a chance at the brass ring again, look for her senate "career" to come to an end as soon as she can manage it.