I think you might have trouble defending your statement about the founding fathers and isolationism. First, one of the primary reasons that the Articles of Confederation were abandoned was that the Britain was flooding America with cheep manufactured goods and putting many northern manufacturers out of Business. One of the important new powers that they gave to the Federal Government was the power to enact tarrifs - which they in fact did on British Goods. Second, in his farewell adress Washington warned about entangling foreign alliances. So, in conclusion, I think there are good arguments that the times have changed since the founder but I don’t think you can make a good faith argument that the founders were not “isolationist” as it is defined by the Free Traders in todays Republican party.
From the very beginning of this country, and even before it was a country, we traded with other countries. We always have. Maybe my definition of isolationism is different than yours. We cannot isolate ourselves from the rest of world, hoping that the two oceans will protect us from harm.