Sad part is that since most social science types know nothing about biology there is very little mentioned about how diseases have affected human history throughout the years. So perhaps the neglect of how diseases were mainly responsible for the de-population of the Indian populations is due (in part) to political correctness but probably mainly through ignorance of even basic biology by historians and political scientists.
Yellow fever decimated native American populations on more than one occasion. The native Americans had never been exposed to it so there was no natural immunity.