But:
The distance between cylinder and cone does vary, even within examples of the same gun. A wide gap is probably most problematic for the greater flash it creates in low light conditions & the crap that builds up because of it.
Smith and Wesson had a bad period quite awhile back. They fixed it but I've never owned an "L" frame since.
Historically, cylinder to barrel flash in the [loose-by-design] powder and ball Colts could be such that the unfired round in the next hole might go off along with the one you'd intended.
[That's an owie]
Any rational shooter will not only work on the cylinder timing (alignment to barrel when the hammer falls) but will have the forcing cone chamfered in order to ease passage of the bullet into the barrel. That improves accuracy, noise, flash, recoil, etc. & such.
Tip of the day:
Don't buy for cheap, invest in quality.
Should read
"Everything Tejeras Slim said"
But I agree with RW on the 30mm revolver anyway.