How did you find the other article in NEJM you were hyping so much? I guess someone gave you a link and you never bothered to search for yourself??
In this ongoing study, subjects were followed for an average of 3 years after the administration of the first dose of vaccine or placebo. In the per-protocol susceptible population, which included 10,565 of 12,167 women who underwent randomization (87%), the vaccine prevented 98% of HPV-16/18–related high-grade cervical lesions (Table 3). In this population, 1 woman in the vaccine group and 42 women in the placebo group received the diagnosis of cervical intraepithelial neoplasia grade 2 or 3 or cervical adenocarcinoma in situ associated with HPV-16, HPV-18, or both. The single subject whose disease was counted as a case (defined as a consensus diagnosis) of HPV-16–positive cervical intraepithelial neoplasia grade 3 in the vaccine group was positive for HPV-52 at baseline as well as in five histologic specimens collected at the time of diagnosis and treatment. HPV-16 DNA was detected in one histologic specimen but at no other time points.Study 2A total of 11,508 of 12,167 women who underwent randomization (95%) were included in the analysis of the unrestricted susceptible population. Vaccine efficacy remained high at 95% (Table 3). Cervical intraepithelial neoplasia grade 2 or 3 or adenocarcinoma in situ developed in 3 subjects in the vaccine group and in 62 in the placebo group. Of note, more than 99% of subjects in this population eventually received the full three-dose regimen.
Subjects in this ongoing trial were followed for an average of 3 years after administration of the first dose of vaccine or placebo. At least 83% of those who underwent randomization were included in one or more of the type-specific, per-protocol susceptible populations for external anogenital or vaginal lesions (2261 subjects in the vaccine group and 2279 in the placebo group). The HPV vaccine was 100% effective (95% CI, 94 to 100; 0 cases in the vaccine group vs. 60 cases in the placebo group) in preventing vaginal, vulvar, perineal, and perianal intraepithelial lesions or warts in association with vaccine-type HPV. In the type-specific, per-protocol susceptible populations, in the analysis for cervical end points, among 2241 subjects in the vaccine group and 2258 in the placebo group, the vaccine was 100% effective (95% CI, 94 to 100; 0 vs. 65 cases, respectively) in preventing cervical intraepithelial neoplasia of grades 1 to 3 or adenocarcinoma in situ in association with vaccine-type HPV (Table 3). The estimates of vaccine efficacy made on the basis of the diagnoses at the central laboratory were similar to the estimates made by the pathology panel (data not shown).More than 95% of the subjects who underwent randomization were included in one or more of the type-specific, unrestricted susceptible populations. The vaccine efficacy was 95% when all grades of external anogenital or vaginal lesions were combined (4 cases in the vaccine group vs. 81 cases in the placebo group), 98% when all grades of cervical lesions were combined (2 vs. 89 cases, respectively), with an efficacy of 91% for high-grade vulvar or vaginal lesions (1 vs. 11 cases, respectively), and 100% for adenocarcinoma in situ (0 vs. 6 cases, respectively) (Table 3). Overall, more than 95% of the subjects received the complete regimen of three doses of vaccine or placebo.
Quite a bit different than the image you're trying to sell.
WHAT is your problem?! I did a search on clinical tests on Gardasil and that's what came up.
THREE YEARS? What are the long term effects? Do you know? Does Merck? Why are they trying to push it on kids? Do you realise that if less than 1% of women get cervical cancer, the test results will be positive for Gardasil because they wouldn't have gotten the disease to begin with?! Do you realise the CDC says most women clear the virus on their own?! Check out Zechariah_8_13s links in post 228
This is a SPECIALTY drug that targets LESS than 1% of the female population. Try doing a search on cervical cancer. It is now rare.
If you want to take unnecessary drugs go right ahead.If you want to feed them to every female that you know, be my guest. But the rest of us have info at our disposal and we aren't buying the "You're all gonna DIE!" line.
http://www.cdc.gov/std/HPV/2004HPV%20Report.pdf
Most infections cause no clinical problems and go away on their own.
Cervical cancer is an uncommon consequence of HPV in women, especially if they are screened for cancer regularly with Pap tests and have appropriate followup of abnormalities.
Try reading the CDCs report to Congress.