[airborne]

If a nuke went off in the US, the world would lose far more than Mecca.

We've lost the courage to bomb Mecca, Medina or any other "holy city".

Things will get much worse first.

[Diogenesis]

Lucky for Osama, Pakistan is Holy and can't be bombed.
Any mosque in which the vermin hides is Holy and can't be bombed.

[M203M4]

We've lost the courage to bomb Mecca, Medina or any other "holy" city.

Fixed. There is moral outrage over putting panties on the heads of terrorists. And forget Heroshima - America, Democrat or Republican, wouldn't have the the political will for even Dresden redux (assuming the responsible nation or nation supporting the responsible group was identified), even if New York was hit with a Big One. Look at the ROE around mosques! In today's political/cultural climate, every hour of WWII would generate a "scandal", speak of "atrocities" and calls for resignations of brass and the arrest of soldiers. And for what? To win an international popularity contest, or to appease the bobble-heads on CNN? Or in a vain attempt to disprove the universal truth that the only humane war is a lost war?

Unfortunately, even if you took all the balls in Washington and combined them into a single pair of frankennuts, there still wouldn't be enough testicular fortitude to even threaten to bomb Mecca (I can think of a few America-first Washington outsiders though...), NYC nuked or not.