Nah. The Alaska experiment, showing that twice as many teens used marijuana in a state that legalized it over the states that didn't. Historical fact, showing that marijuana use in the late 70's was triple what it was at its lowest point.
I remember reading about rampant drug abuse of all types, including huffing gasoline among the Eskimo tribes. Are you sure you're not cherry picking some statistical data to lead to a pre-determined conclusion? I'm not.