This is a fairly high dosage, considering that the average off-the-shelf pill is no more than 200mg, although prescriptions can range to 800 mg. Nonetheless, an interesting study.
Another excuse to stick with my favorite pills in the world- Vicodin.
My mom is prescribed 2400mg (3 800mg pills) per day. Since Vioxx was taken off the market, more and more people have been prescribed high doses of ibuprofen. (If one doesn’t kill you, the other will.)
This has me worried, since she has been short of breath with relatively low levels of activity. I am going to suggest (vehemently) she see her doctor again, since my dad had similar symptoms just before he died of a massive heart attack.
She has a bad combination of high blood pressure and severe arthritis in her knees.
200mg tablets, Recommended "1 tablet every 4 to 6 hours, not to exceed 6 tablets in a 24 hour period".
So, if you double the dosage over an extended period of time, it's bad for you. Makes sense to me.