I think Randy compares apple with bananas.
The 787-8F can carry 140 t payload at a range of about 8.000 km. The A380F carry 150 t more than 10.000 km. Up to this range the 787-8F can only carry 110 t.
But what does FedEx, UPS or DHL needed most - mass or volume? The Airbus can handle 1.7 times more volume.
And no doubt for Randy on an Airbus containers are more than one and half times heavier than on a Boeing.
Look at the numbers he uses (he says 380 #'s are Airbus' claim).
With the figures in the graphic, the max dry weight (minus tare) of the -8F is 312; 393 for the 380F.
That translates to a Revenue Payload fraction for the -8 of 43%; 36% for the 380F. This is NOT MTOW; this is max DRY WEIGHT (minus tare) from the numbers in the graphic.
And no doubt for Randy on an Airbus containers are more than one and half times heavier than on a Boeing.
There is NO doubt that the A 380 F has three cargo decks vs two on the 747-8F, and the -8F has big doors and 'full frontal' loading. The 380F will certainly need more containers for 3 decks vs 2, and perhaps one and half times more 'tare' per trip! It will also take longer to load; perhaps much longer.
So then it would seem that the 747-8F will burn a lot less fuel per tonne/mile than the 380F, and the longer the route, the greater the trip cost difference.
These are raw, rough numbers, but they are certainly valid in this comparison, no?