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To: Caesar Soze
who wouldn't want a vaccine to reduce the chance of getting cancer in their equipment?

No one of course, but that isn't the issue.

The issues are

(1) Has the link between the virus that causes warts and the virus that causes cervical cancer been established?
I am unaware of any peer reviewed articles published. If you know of any, please share them

(2) Does the vaccine do what they say it does? Cleared by the FDA just means it's (relatively) safe. The CDC is supposed to determine if it's necessary, and has issued no recommendation.

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The State of Texas recently went directly against the CDC's recommendation for Acanthosis Nigricans screening, yet the State used the newly-created Texas-Mexico Border Health Coordination Office at the University of Texas-Pan American in order to implement it.

Why do the Governor and the State legislators think they have the medical ability to override (or blindside) the highest acknowledged medical authority in the nation?

144 posted on 02/05/2007 11:21:23 AM PST by MamaTexan (I am not an administrative, public, or legal 'person'.....and neither are my children!)
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To: MamaTexan
(1) Has the link between the virus that causes warts and the virus that causes cervical cancer been established? I am unaware of any peer reviewed articles published. If you know of any, please share them

My school's database is slow during the day, and I'm not really one for biology, but here's a few articles to start you out:

Parkin. Int J Cancer. 2006 Jun 15;118(12):3030-44. The global health burden of infection-associated cancers in the year 2002.

Cancer and the Immortal Strand Hypothesis. John Cairns. Genetics. Bethesda: Nov 2006.Vol.174, Iss. 3; pg. 1069
How HPV may cause cancer by deactivating genes that detect damaged DNA.

Solution structure of the partially folded high-risk human papilloma virus 45 oncoprotein E7. O Ohlenschläger, T Seiboth, H Zengerling, L Briese, et al. Oncogene. Basingstoke: Sep 28, 2006.Vol.25, Iss. 44; pg. 5953
"Direct evidence" of the interaction between the cancer-related HPV protein and the host's cells.

Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model Katerina Strati, Henry C Pitot, Paul F Lambert. Proceedings of the National Academy of Sciences of the United States of America. Washington: Sep 19, 2006.Vol.103, Iss. 38; pg. 14152
Researchers give mice HPV, mice get cancer.

The Tango and Tangle of Human Papillomavirus and the Human Genome. Robert D. Burk, Rob DeSalle. Journal of the National Cancer Institute. Oxford: Aug 2, 2006.Vol.98, Iss. 15; pg. 1026
Abstract: Human papillomavirus (HPV) oncogenic types, especially type 16, are some of the most potent human carcinogens described. The odds ratio of squamous-cell cancer in HPV16-infected women has been estimated to be 435 (95% confidence interval [CI] = 278 to 679) and appears to be high throughout the world. The public health burden of both HPV and cervix neoplasia is profound; cervical cancer is the second most prevalent cancer in the developing world with nearly half a million cases diagnosed per year.

(2) Does the vaccine do what they say it does? Cleared by the FDA just means it's (relatively) safe. The CDC is supposed to determine if it's necessary, and has issued no recommendation.

You propose two questions here. 1: Does it doe what they say it does? And 2: Is it necessary? The answer to the first is, "Yes, for at least a few years." You can see that in the FDA link I provided above and the CDC link below. The answer to the second is a public health question, and depends on what you consider necessary. Many people don't consider seat belts, fluoridated toothpaste, or the Second Amendment necessary -- sometimes the government has to override those opinions.

And if you have access to JAMA, you may enjoy this, since it touches on the CDC and the public health aspects of HPV infection:
CDC Panel Backs Routine HPV Vaccination. Bridget M Kuehn. JAMA. Chicago: Aug 9, 2006.Vol.296, Iss. 6; pg. 640

Abstract: A vaccine that has been shown to prevent cervical cancer, precancerous genital lesions, and genital warts may soon become part of the schedule of vaccinations for preteen girls if leaders of the Centers for Disease Control and Prevention (CDC) and the Department of Health and Human Services follow the recommendation of a CDC scientific advisory panel. In June, the CDC's Advisory Committee on Immunization Practices voted unanimously to recommend that girls aged 11 to 12 years be routinely vaccinated against the human papilloma virus (HPV).

You may read the minutes of that meeting here.

157 posted on 02/05/2007 11:57:18 AM PST by Caesar Soze
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