Another interesting fact is that antiangiogenic agents, contrary to intution, enhance the effectiveness of cytotoxic (chemotherapy) agents by increasing their concentration in the tumor. This according to research by Dr. Bevery Teicher.
Thanks for posting these very interesting articles.
Fascinating stuff. Have multiple friends and family (in-laws) undergoing cancer treatment right now. This will most likely be too late for some of them, but it gives me hope for the future.
Though Entremed terminated Endostatin production in 2003 due to the extremely high cost a Chinese researcher, Dr. Luo Yongzhang, has identified the molecule, mastered the protein folding technique, and his company is now producing its own version, Endostar, at cheaper production costs (link).
It is a very exciting area of cancer research.