It doesn't say just they must have the same number of senators, it says
no State, without its Consent, shall be deprived of its equal Suffrage in the Senate.That's stronger. If a senator is incapacitated, and can not vote, that means that senator's state is being denied equal suffrage in the Senate!
Hmmm...has a governor (or state government in any capacity) ever pushed the issue?
The House of Representatives did press the issue.
I recall the case of
Gladys Noon Spellman (March 1, 1918—June 19, 1988)
On October 13, 1980, Spellman collapsed at a children's Halloween costume party after suffering an incapacitating heart attack, rendering her comatose for the final years of her life. House Resolution 80 of the 97th Congress, adopted February 24, 1981, declared her seat vacant. Steny Hoyer was subsequently chosen in a special election to fill the vacancy.
en.wikipedia.org/wiki/Gladys_Noon_Spellman
Any others? I am inclined to think that the Senate would have to declare the seat vacant.