The surest way of taking out the Commerce Clause garbage is by Amendment. Alas, Amendments are really hard. In 230 years we have an average of what, one every 8 years? I wonder, what would be your short list of amendment worthy SCOTUS errors?
Maybe, but it turns the idea of a government of limited, enumerated powers upside down and establishes the precedent of a goverment of limited, enumerated restrictions. It would become incumbent on the States to explicitly reserve for themselves whatever power they didn't want the federal government to assume.