Islam forbids representations of Muhammed. Islam tends to be an iconoclastic religion. At various times and places, Muslims have permitted artists to depict persons and scenes. But the strictest versions of Islam disallow any kind of painting, and in particular depictions of Muhammed.
There are exceptions, even in that case. But no one would dare make a movie about Muhammed in which an actor actually played the part, because there would be riots, burnings, and retribution against the makers of the film. I believe Hollywood did make a movie about Islam, but without actually showing Muhammed.
In any case, if you had a movie about Muhammed, it would most likely be politically correct and gloss over the real details.
I could see somebody making a porn movie about Mad Mo and his harem. But he would have to do it under an alias and make very sure he was never found