No I am not. I so stated. The gene for lactase is present and functional. A mutation does not "disable" that gene in the condition that we are discussing. What is "disabled" is the switching off of that gene. This gives the possessor of that mutation the ability to keep digesting the lactose later on in life. If you had read the article which I had posted you would also have realized that was mentioned in this.
Olds and Sibley (2003) characterized the functional role of the C/T(-13910) and G/A(-22018) (601806.0002) polymorphisms in regulating lactase gene transcription. Human intestinal cells were transfected with variant/promoter-reporter constructs and assayed for promoter activity. A 200-bp region surrounding the -13910C variant, associated with lactase nonpersistence, resulted in a 2.2-fold increase in lactase promoter activity. The -13910T variant, associated with lactase persistence, resulted in an even greater increase. The DNA sequence of the C/T(-13910) variants differentially interacted with intestinal cell nuclear proteins. The authors concluded that the DNA region of the C/T(-13910) lactase persistence/nonpersistence variant functions in vitro as a cis element capable of enhancing differential transcriptional activation of the lactase promoter.
Au contraire, it is not 'returned'. It never left in those individual genomes where the shut-down sequence is disabled.
You did not understand what I stated, because you are merely repeating what I stated. The quotes I put around the words I post are there for a reason.
What we are dealing with here is a complex system
Exactly my point. Look at my post 79. You are considering the situation as in figure one. I am explaining that the situation is like that in figure 3.
Yes, I know that. That's why I said the 'shut-down' sequence is disabled. The article I posted said that the change was in a regulatory site located close to the lac gene. I never said it was the lac gene.
"Exactly my point. Look at my post 79. You are considering the situation as in figure one. I am explaining that the situation is like that in figure 3."
And my point is that breakdowns in complex systems (including regulatory systems) are loss-of-function mutations that cannot be used to support evolution. IF, AND, and THEN operands are signs of intelligent-design in a complex system.