Thank you, I have done extensive reading on this subject. In 1918, the flu was most rampant in military barracks, ships, and other areas where humans were in very close proximity. Asymptomatic individuals died within 24 hours. Personal hygiene was atrocious by current standards. The most effective containment method was quarantine.
I do remember the "Swine Flu" pandemic. Many people from the NIH, including Richard Krause, have studied this and written extensively on the subject. Here is an excerpt, and an applicable link:
"The 1918 influenza pandemic has shaped research and public health for nearly a century. In 1976, the specter of 1918 loomed large when a pandemic threatened the country again. Public health officials initiated a mass vaccination campaign, but the anticipated pandemic failed to occur. An examination of the available data in 1976 and the decision to vaccinate, as well as lessons learned from the HIV/AIDS epidemic in the early 1980s, may help shape an appropriate public health response to future threats from avian influenza or other infectious diseases."
http://www.cdc.gov/ncidod/EID/vol12no01/05-1132.htm
It is worth noting that this was published in 1998.
Then you must be aware that there is no vaccine for H5N1 in humans.