I used to subscribe to Reason, but I dropped it a few years ago when it slid into the confines of "leftist rag". The really took a bad turn when Bush was elected, and not just on economic issues (which are fair game IMHO). It was as if Howard Dean had a hand in writing articles for the magazine.
I quit when Virginia Postrel left the mag. Those that replaced her lacked her grace and the magazine tanked in its tone. Too much snideness and condesencion for me from the new editorial regime.