"If you experience sudden INVOLUNTARY MOVEMENTS on the drug, you may need a lower dose."
http://www.usnews.com/usnews/health/brain/parkinsons/park.treat.drugs.dopreplace.htm
True enough. All I can say though is that it can be a difficult thing to avoid later in the disease. Back when I was still seeing a fair number of PD patients, several years ago, sinemet was still widely used. new onset patients might get 25/100 TID plus an extra one here or there if symptoms recurred but over time the dose would have to be escalated to achieve the same effect and then spread out into lots of little doses to avoid the "on" state. Dopamine agonists could be used to smooth things out and avoid some of the on state symptoms. Now the main centers are using dopamine agonists as first line treatments which delays the onset of "on" state issues but eventually even with those problems can occur.