There's a program that just came on the Discovery Channel titled: Ice Age Columbus: Who were the first Americans? Looks interesting, it starts out in Iberia, hee, hee.
There are those who believe the Sa'ami "wintered over" in NW Scandinavia during the last glacial maximum.
Seems it never iced up ~
During that period of time they became somewhat "different" from the other European people, and vice versa.
Although some of the genetic differences are identified as disease, what we are talking about in modern times with modern populations is a statistical norm with some folks ending up with a bunch of "different" genes they didn't even know were in the family.
Northern European "problems" traced to Sa'ami origins are celiac disorder, Scandinavian porphyria (3 different genes for that one), extra sinus nodes in the heart muscle, varities of type II diabetes, and so on. I think a double count of red cones in the retina is part of the "package" as is the elimination of blue cones. THat way you can see a small fire many miles across the ice in the darkest of night.
All of these "conditions" are actually very normal for a population that never eats wheat, barley or rye, has only low glycemic index vegetables available, survives on high fat fish and sea mammals, and lives through a Polar winter many months long.
Eskimos have the same "problems".