I believe that the first rule of gunfighting is that you must bring a gun. My first choice will probably always be a 1911, but if an SAA is your favorite, and that's what you have with you, the first rule has been met. If you know how and when to use it, it'll work.
I'm a 1911 fan, too, but I do enjoy shooting a SAA .45 "Long" Colt revolver. The Uberti models in my post above were from the Uberti website.
I also like the Ruger Vaquero revolvers, too.
Also, never go to a gunfight with a pistol with a caliber that doesn't start with a "4." As noted above, reload time with a single-action wouldn't make the cut with me. But then I am a certified (thankfully NOT certifiable) 1911 shooter. I own three Colt Gold Cups (Series 70 National Match for me only, thank you) so you can tell I have the bug pretty bad. I could be talked into one of the Colt clones, but I do like the real deal. ;>)
Almost as important as bringing a gun is bringing one that you are confident with.
I have my father's 1911 (sn 161636). It's a old one. Has probably had a 100,000 rounds run thru it. Dad could knock a fly off a dog's nose at 25 yards and not cause a rash--night or day, either hand. I missed a possum 7 times from under 15 feet one evening--braced with a two-handed grip. I tend to roll my wrist when I squeeze a slab-side. Not something I'm proud of and a source of endless humor for my wife and boys.
My primary defense weapon is a 5-shot .38 revolver. I'm good with it. I'm confident that I will hit my intended target. Am I concerned that I may only get 5 shots off? Sure. But I know I'll hit somebody 5 times. I doubt I could hit somebody 5 times with a fully loaded Glock 21.
Guess it falls under the old "a man's gotta know his limitations" thing.