"Most of what you eat is a result of polyploidy within historical times (< 10,000 years ago)."-JS1138
polyploid Âadjective 1. having a chromosome number that is more than double the basic or haploid number. polyploidy n : the condition of being polyploid
So? How did this result in evolution having a practical use? I hope you aren't suggesting that breeding experiments prior to evolutionary theory even existing were the result of evolutionary theory being applied by scientists.
You asked about macro-evolution, and I gave examples of known instances that have proven useful. Many of the instances have been selected by humans after occurring naturally.
We know they occurred after human cultivation started because they can't sustain themselves without cultivation.
Now you can quibble about the naturalness of this, but the fact is that until recent decades, all such mutations were natural, and humans simply changed the rules for selecting which variants got to produce the most offspring.
The principles of evolution can be useful without being written down in books, just as people could make music befor the invention of notation.