Larry King asks " how do you defeat an enemy that is willing to kill itself?" Hold their entire families responsible....
What they do to us should be done to 'every' identifiable relative they have . On a wider scale ; tell them now , tell them loud and clear " If you nuke us we WILL nuke Mecca , Medina , Tehran, and Qom "
Show them no quarter
Do NOT wait until they destroy a city, or kill thousands more. Decapitate the Iranian regime, and destroy their nuke sites RIGHT NOW, and do it with nukes (the only sure way to get it all).
Do not invade, simply tell the Iranians that we listened to their leaders, believed that they meant what they said, and took appropriate action. "Now, find yourselves some better leaders please!"
Lather, rinse, repeat as necessary!