For some with allergies (a few members of my family), a stay in a room with even a slight smoke smell can be extremely unpleasant.
Absolutely true...
An allergic reaction requires protein.
There is no protein in tobacco smoke.
What you are describing is hysteria.
"For some with allergies (a few members of my family), a stay in a room with even a slight smoke smell can be extremely unpleasant."
For some with allergies, the smell of cleaning products, room deodorizer, fabric softener, or lingering scent of perfume can be extremely unpleasant.