Only if you allow them to.
Hiding your head in the sand just leaves your ass exposed for a good kicking.
Actually, it is the Globalist Kown-It-All BusyBodies who exposes our country...and the innocents who never signed up for this ride... to a good ass-kicking from one end of the planet to the other.
How are you gonna stop them? Ban international trade and travel? Forbid our citizens to venture beyond our borders? Suppress any inventions discovered here from being used there, and vice versa? Shut down the Internet?
Even if you did these things, how long before an expansionist outsider who hadn't crippled their trade outstrips us and imposes its will? You can't hide from the rest of the world, nor stand aloof. It will not let you. Washington had the luxury of an ocean crossed by sailboats to protect his right flank from the world, and a nearly uninhabited Continent on his left. Today, both can be crossed at lightspeed. And you can't stop it.