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Hmmmm ...

Are "Ligers" fertile? How about your cat?

This polar/grizzly cross is ... mules are not.

When they start out with the Asian leopard and the domestic Egyptian Mau typically the resulting MALE (F1) is infertile. The females are fertile. So you take it from there. A generation or so removed from the parents and males are then typically fertile and the breed continues. Also an F1 kitten of this mix is not appropriate for a pet. It's too wild and you need an experienced breeder to ONLY continue the breed with descendent's of good temperament, looks etc.. Like anything else, you MUST deal with a reputable breeder.

As for Ligers I believe the same scenario is true on the issue of male/female infertility. There is no reason why this mix could not continue.