Sure do. And that is the reason we see so many drugs pulled off the market. Hey, monkeys didn't die so humans shouldn't either. Wow. Five people killed in how many years? Oh, 50 or 100? Guess what. Anthrax virus was all supposed to be accounted for. Maybe we should be concerned about how it got out there more than what it could do if it does get out there. Seems a more plausible approach to me. Maybe we should store serum for the Black Plague. Never know when a terrorist will hit us with that.
Sure do. And that is the reason we see so many drugs pulled off the market.
Drug development and withdrawal from the market have nothing to do with vaccine development.
Hey, monkeys didn't die so humans shouldn't either.
Ethical human trials are problematic, especially for airborne anthrax. Because of that, it may only be tried in a suspected anthrax attack.
Wow. Five people killed in how many years? Oh, 50 or 100?
Five people were killed during the fall of 2001 from the same weaponized strain, IIRC.
Guess what. Anthrax virus was all supposed to be accounted for.
Smallpox virus was supposed to have been eliminated except for reference specimens retained securely by the U.S. and the U.S.S.R. Anthrax, i.e. bacillus anthracis, is a bacterium endemic to several areas around the world, including the southwest of the U.S.
Systematic review: a century of inhalational anthrax cases from 1900 to 2005.
BACKGROUND: Mortality from inhalational anthrax during the 2001 U.S. attack was substantially lower than that reported historically. PURPOSE: To systematically review all published inhalational anthrax case reports to evaluate the predictors of disease progression and mortality. DATA SOURCES: MEDLINE (1966-2005), 14 selected journal indexes (1900-1966), and bibliographies of all retrieved articles. STUDY SELECTION: Case reports (in any language) between 1900 and 2005 that met predefined criteria. DATA EXTRACTION: Two authors (1 author for non-English-language reports) independently abstracted patient data. DATA SYNTHESIS: The authors found 106 reports of 82 cases of inhalational anthrax. Mortality was statistically significantly lower for patients receiving antibiotics or anthrax antiserum during the prodromal phase of disease, multidrug antibiotic regimens, or pleural fluid drainage. Patients in the 2001 U.S. attack were less likely to die than historical anthrax case-patients (45% vs. 92%; P < 0.001) and were more likely to receive antibiotics during the prodromal phase (64% vs. 13%; P < 0.001), multidrug regimens (91% vs. 50%; P = 0.027), or pleural fluid drainage (73% vs. 11%; P < 0.001). Patients who progressed to the fulminant phase had a mortality rate of 97% (regardless of the treatment they received), and all patients with anthrax meningoencephalitis died. LIMITATIONS: This was a retrospective case review of previously published heterogeneous reports. CONCLUSIONS: Despite advances in supportive care, fulminant-phase inhalational anthrax is usually fatal. Initiation of antibiotic or anthrax antiserum therapy during the prodromal phase is associated with markedly improved survival, although other aspects of care, differences in clinical circumstances, or unreported factors may contribute to this observed reduction in mortality. Efforts to improve early diagnosis and timely initiation of appropriate antibiotics are critical to reducing mortality.
Do me a favor. Keep your idle, uninformed comments off of my medical threads, please. I will no longer dignify them with any replies if I can avoid it.