Midnight...time for my aspirin.
Cold-Eeze works for me and my family EVERY time. No kidding. The zinc fights off the virus.
For best results, mix with Grey Goose Vodka.
The other way to do it would be to let the body's natural processes take over.
In other words, remember that a fever is not a disease, it is actually a symptom of the body preventing viruses from replicating. When the body temperature goes above 101 degrees viral replication is shut down. This helps the immune system because it cuts down on the number of viruses the immune system will eventually have to erdicate.
But during the first few days of the viral infection the body is preparing the immune system to attack that specific virus, and if you skip the step of letting your body produce a fever then you leave the virus alone to replicate in vast numbers. Then when it has replicated virtually unchecked for a few days it can seriously overwhelm the immune system.