Yes, and there was plenty of persecution of Catholics, especially Irish, as a result of the phony notion that the Pope was somehow going to interfere in US policy.
Would you feel the same way about the Church if priests and bishops broke the law regarding violating privacy zones around abortion clinics?
And it wouldn't be such a phony notion after all if the Pope told Catholics to aid illegal aliens in violation of US laws, and they did it.
As for protest laws, I question the constitutionality of those, but people who violate ones that pass the test should be prepared to suffer the consequences (usually a night in jail or small fine).