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Treating carotid blockage may reverse dementia (reverse cholesterol, get smart)
Reuters Health ^ | 2006-03-31 | Karla Gale

Posted on 04/01/2006 11:06:28 AM PST by ConservativeMind

Patients who have blocked carotid arteries, the major source of blood flow to the brain, even if there are no symptoms, experience significant improvements in intellectual functioning after they undergo surgery to correct this problem, investigators reported Friday at the Society of Interventional Radiology's annual meeting in Toronto.

In fact, younger patients and those who have not had a stroke appear to experience the most benefit from the procedure. Carotid stenting involves placement a "stent," a device use to prop open the blocked vessels. Strokes can occur when plaques that have formed in the carotid arteries, which lie on each side of the neck, break off or otherwise obstruct blood flow to the brain.

"What we found was earth-shaking," presenter Dr. Rodney D. Raabe, of Sacred Heart Medical in Spokane, Washington, told Reuters Health. The findings will change the way we think about carotid artery disease, how it is treated and how patients are classified.

He pointed out that his group's initial goal was to show that using a protective filter during carotid artery stenting would prevent decline of mental function after the procedure.

The study included 40 patients, half of whom were considered to be symptomatic -- meaning that they had carotid artery blockage and a previous stroke or neurologic event -- and half were asymptomatic, but also had artery blockage.

"So far, we've conducted 6-month evaluations on 30 patients with an extensive battery of neurocognitive tests," Raabe explained. "Remarkably, they all showed significant cognitive improvement, especially in executive function, their ability to think abstractly, make judgments and reason."

In fact, he added, "some patients whose functioning was so poor that they were being considered for nursing home placement, are now doing quite well living independently at home. This study shows that people, even before they have a stroke, are probably not functioning as well as they could be."

Currently, the only reason carotid artery blockages are treated in the US is to prevention stroke. However, if these results are repeated in larger studies, it will show that patients who have more than an 80 percent blockage are not asymptomatic, "they do have symptoms, but it takes complicated testing to measure it," the researcher said.

He believes patients with early dementia may actually be experiencing the results of blocked carotid arteries and that their condition can be reversed. "They should be looked at to see if they have an asymptomatic blockage.

In the future, we probably won't wait so long to treat patients with narrowing of the carotid artery because they're showing functional neurocognitive impairment, and they'll think better once we treat them."


TOPICS: Culture/Society; Miscellaneous; News/Current Events
KEYWORDS: cardiovascular; carotid; carotidartery; endarterectomy
This could provide an incredible opportunity to increase the quality of life and reduce costs for those approaching old age.

It also serves to remind us that taking care of ourselves and reducing cholesterol plaques (eating right, exercise, reduce stress, take policosanol and cinnamon, possibly use statins, etc.) means we stay smarter and more alert without fear of old age and its common mental decline.

1 posted on 04/01/2006 11:06:29 AM PST by ConservativeMind
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To: ConservativeMind
eating right, exercise, reduce stress, take policosanol and cinnamon, possibly use statins, etc.

Agree, but thems fightin' words round here.

2 posted on 04/01/2006 11:08:38 AM PST by King Moonracer
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To: ConservativeMind

I worked in a hospital for years. Whenever a patient got angry or was difficult, the nurses would call the doctor and ask for a blood gas. Almost always it was low.

Since then I have run into many people who are just difficult, who I think are really having O2 problems. Unfortunately, most people just don't "get it".


3 posted on 04/01/2006 11:11:57 AM PST by I still care ("For it is the doom of men that they forget" - Merlin, from Excalibur)
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To: ConservativeMind
My father had had a carotid endarterectomy performed in 1995. He's very lucky he didn't have a major stroke before that procedure was done.
4 posted on 04/01/2006 11:12:10 AM PST by Paleo Conservative
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To: King Moonracer
Agree, but thems fightin' words round here.

Yep. They target the "Southern Way of Life" even more surely than Yankee Carpetbaggers did during Reconstruction. ;)

5 posted on 04/01/2006 11:18:42 AM PST by Mr. Jeeves ("When the government is invasive, the people are wanting." -- Tao Te Ching)
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To: Mr. Jeeves
You know, you can eat right most of the time and once in a while have a burger or something similar without ill effects.

I am on a low dose statin. I was hesitant, but then read an article which said they believe it also helps prevent Alzheimer's disease. That was enough for me! I went and filled that prescription the same day.

6 posted on 04/01/2006 11:23:17 AM PST by Miss Marple (Lord, please look after Mozart Lover's and Jemian's sons and keep them strong.)
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To: ConservativeMind

Eat, sleep, work and exercise smart takes new meaning.


7 posted on 04/01/2006 11:39:52 AM PST by UnbelievingScumOnTheOtherSide (Give Them Liberty Or Give Them Death! - IT'S ISLAM, STUPID! - Islam Delenda Est! - Rumble thee forth)
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To: ConservativeMind

Maybe this is what Cynthia McKinney needs.


8 posted on 04/01/2006 12:00:55 PM PST by msnimje (SAMMY for SANDY --- THAT IS WHAT I CALL A GOOD TRADE!!!)
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